Quizartinib (AC220) cas:950769-58-1
Quizartinib (AC220)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-976 | 100mg | 215.00 | + Add to cart |
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R-C-976 | 200mg | 375.00 | + Add to cart |
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R-C-976 | 500mg | 700.00 | + Add to cart |
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Product description
Quizartinib(AC220)is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor,with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM,respectively.Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader.Quizartinib induces apoptosis.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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