Pyridone 6 CAS:457081-03-7

Pyridone 6(CMP 6)is a potent and selective inhibitor of JAK1 (IC50=15 nM,murine JAK1),JAK2 (IC50=1 nM),JAK3 (Ki=5 nM),and Tyk2 (IC50=1 nM);displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.

msds---Pyridone 6