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PKI-179 hydrochloride CAS No.1463510-35-1
PKI-179 hydrochloride CAS No.1463510-35-1
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1201 | 10mg | 380.00 | + Add to cart |
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| R-R-1201 | 25mg | 780.00 | + Add to cart |
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Product description
PKI-179 hydrochloride/CAS No.1463510-35-1 is a potent and orally active dual PI3K/mTOR inhibitor, with IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR, respectively. PKI-179 hydrochloride also exhibits activity over E545K and H1047R, with IC50s of 14 nM and 11 nM, respectively. PKI-179 hydrochloride shows anti-tumor activity in vivo.
| Appearance | N/A |
|---|---|
| Molecular Weight | 525.00 |
| Purity | >90% |
| CAS | 1463510-35-1 |
| Formula | C25H29ClN8O3 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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