PHA-767491HCL CAS:942425-68-5
PHA-767491HCL
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
---|---|---|---|---|
R-C-1341 | 100mg | 215.00 | + Add to cart |
|
R-C-1341 | 200mg | 525.00 | + Add to cart |
|
R-C-1341 | 500mg | 900.00 | + Add to cart |
|
|
Product description
PHA-767491,also known as CAY10572,is a potent,ATP-competitive dual cdc7/cdk9 inhibitor(IC50 values are 10 and 34 nM respectively)that prevents initiation of DNA replication.PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.PHA-767491 in combination with 5-FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP-Ribose)polymerase fragmentation in HCC cells.
Appearance | N/A |
---|---|
Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
Document
Related Product