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PEGylated DOPC/CHOL Liposomes labeled with DiO,100nm
PEGylated DOPC/CHOL Liposomes labeled with DiO
Product description
PEGylated DOPC/CHOL liposomes labeled with DiO offer a versatile platform for drug delivery and imaging applications.
The fluorescent control liposomes contain the green lipophilic dye DiO incorporated in the bilayers. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc.
The green fluorescent, lipophilic carbocyanine DiOC18(3) is widely used as a lipophilic tracer. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.
Appearance | N/A |
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Lipid Composition | DOPC/CHOL/mPEG2000-DSPE (50:45;5 mol/mol) |
Lipid concentration | 50 mM (50-55 mM) |
Dye | 0.5 mM (0.44 mg/mL) |
Mean particle size (z-average) | 100nm (85-110nm) |
Hydration buffer | 10% sucrose, 20mM HEPES, pH 7.3 ± 0.2 |
Storage | 4 ° C,protected from light and moisture (do not freeze) |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 6 months |
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