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Nirogacestat (PF-03084014) CAS:1290543-63-3

Nirogacestat (PF-03084014)

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-1393 10mg 125.00
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R-C-1393 50mg 520.00
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R-C-1393 100mg 920.00
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Product description

Nirogacestat,also known as PF-03084014,is a potent and selective gamma secretase (GS)inhibitor with potential antitumor activity.PF-03084014 binds to GS, blocking proteolytic activation of Notch receptors.Nirogacestat enhances the Antitumor Effect of Docetaxel in Prostate Cancer.Nirogacestat enhances docetaxel-mediated tumor response and provides a rationale to explore GSIs as adjunct therapy in conjunction with docetaxel for men with CRPC(castration-resistant prostate cancer).


Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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