Nirogacestat (PF-03084014) CAS:1290543-63-3
Nirogacestat (PF-03084014)
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-1393 | 10mg | 125.00 | + Add to cart |
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| R-C-1393 | 50mg | 520.00 | + Add to cart |
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| R-C-1393 | 100mg | 920.00 | + Add to cart |
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Product description
Nirogacestat,also known as PF-03084014,is a potent and selective gamma secretase (GS)inhibitor with potential antitumor activity.PF-03084014 binds to GS, blocking proteolytic activation of Notch receptors.Nirogacestat enhances the Antitumor Effect of Docetaxel in Prostate Cancer.Nirogacestat enhances docetaxel-mediated tumor response and provides a rationale to explore GSIs as adjunct therapy in conjunction with docetaxel for men with CRPC(castration-resistant prostate cancer).
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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msds-----Nirogacestat (PF-03084014)
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