Monodansylcadaverine,cas:10121-91-2

Monodansylcadaverine (MDC) is a fluorescent probe that is used for detecting autophagy in the cytoplasm and vacuoles of plants and mammalian cells via marking the autophagosomes. Study revealed that monodansylcadaverine acts as a lysosomotropic agent, being concentrated into acidic compartments by an ion-trapping mechanism, and as a solvent polarity probe, increasing its relative fluorescence intensity by interacting with membrane lipids that are highly concentrated in the autophagic vacuoles.

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