Mivebresib (ABBV-075) CAS:1445993-26-9
Mivebresib
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-1562 | 50mg | 365.00 | + Add to cart |
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| R-C-1562 | 100mg | 700.00 | + Add to cart |
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| R-C-1562 | 200mg | 1150.00 | + Add to cart |
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Product description
Mivebresib(ABBV-075)is a novel BET family bromodomain inhibitor.It binds bromodomains of BRD2/4/Twith similar affinities(Ki of 1-2.2nM)and highly selective for 18 bromodomain proteins tested (Kd>1μM;more than 600-fold selectivity vs.BRD4),but exhibits roughly 10-fold weaker potency towards BRD3 (Ki of 12.2 nM)and has moderate activity towards CREBBP(Kd=87μM;54-fold selectivity vs.BRD4).Mivebresib(ABBV-075)efficiently triggers apoptosis in various tumor cell.
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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