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Mivebresib (ABBV-075) CAS:1445993-26-9

Mivebresib

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-1562 50mg 365.00
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R-C-1562 100mg 700.00
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R-C-1562 200mg 1150.00
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Product description

Mivebresib(ABBV-075)is a novel BET family bromodomain inhibitor.It binds bromodomains of BRD2/4/Twith similar affinities(Ki of 1-2.2nM)and highly selective for 18 bromodomain proteins tested (Kd>1μM;more than 600-fold selectivity vs.BRD4),but exhibits roughly 10-fold weaker potency towards BRD3 (Ki of 12.2 nM)and has moderate activity towards CREBBP(Kd=87μM;54-fold selectivity vs.BRD4).Mivebresib(ABBV-075)efficiently triggers apoptosis in various tumor cell.

Mivebresib (ABBV-075)   CAS:1445993-26-9

Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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