mPEG5K-b-PDPA17K

Block copolymer micelles are usually formed by self-assembly of amphiphilic block copolymers in aqueous media.Hydrophilic and hydrophobic blocks form shell and core micelles,respectively.Methoxypolyethylene glycol(MPEG)-b-Poly(2-diisopropylamino)ethyl methacrylate(PDPA)block copolymer was synthesized by atom transfer radical polymerization of 2-bromoisobutyl bromide and MPEG in the presence of triethylamine catalyst.Atom transfer radical polymerization of diisopropylethyl methacrylate (diisopropylethyl ethyl methacrylate) was carried out in DMF at 70℃ with artificial neural network(ANN) and N,pentamethyldiethylenetriamine-copper bromide catalyst system.The pH induced micellization-decellularization was studied by fluorescence method and pyrene probe.

msds---mPEG5K-b-PDPA17K