Mal-PEG4-trimethylammonium chloride

Mal-PEG4-trimethylammonium chloride is a versatile reagent that combines the benefits of maleimide-mediated bioconjugation with the properties of polyethylene glycol (PEG) and cationic trimethylammonium groups.

The maleimide functionality allows for selective conjugation of fluorescent dyes, drugs, or other molecules to proteins, enabling their use in imaging, tracking, or therapeutic applications.The positively charged trimethylammonium can facilitate the formation of nanoparticles or complexes that enhance the delivery of nucleic acids (like DNA or RNA) or other therapeutics into cells.

The compound can be used to create ADCs by linking a cytotoxic drug to an antibody via the maleimide group, allowing targeted delivery of the drug to cancer cells.It can be used to modify surfaces of medical devices or scaffolds to improve biocompatibility or enable further functionalization.

msds of Mal-PEG4-trimethylammonium chloride