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M77976,cas:394237-61-7

4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-XASYS-00534 5mg 459.00
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R-XASYS-00534 10mg 826.00
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Product description

M77976(C17H16N2O3,296.32) is a PDK4 inhibitor (human pyruvate dehydrogenase kinase 4). M77976 binds to the ATP-binding pocket of PDK4 and causes local conformational changes with complete disordering of the ATP lid. M77976 binding also leads to a large domain rearrangement that further expands the active-site cleft of PDK4 compared with the ADP- and AMPPNP-bound forms.

M77976,cas:394237-61-7

Appearance N/A
Molecular Weight N/A
Purity >90%
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 1 year
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