M77976,cas:394237-61-7
4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-XASYS-00534 | 5mg | 459.00 | + Add to cart |
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R-XASYS-00534 | 10mg | 826.00 | + Add to cart |
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Product description
M77976(C17H16N2O3,296.32) is a PDK4 inhibitor (human pyruvate dehydrogenase kinase 4). M77976 binds to the ATP-binding pocket of PDK4 and causes local conformational changes with complete disordering of the ATP lid. M77976 binding also leads to a large domain rearrangement that further expands the active-site cleft of PDK4 compared with the ADP- and AMPPNP-bound forms.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >90% |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
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