LY2835219 CAS:1231929-97-7
LY2835219
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-1064 | 100mg | 135.00 | + Add to cart |
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R-C-1064 | 200mg | 175.00 | + Add to cart |
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R-C-1064 | 500mg | 345.00 | + Add to cart |
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Product description
LY2835219 mesylate is a potent and selective CDK4/6 dual inhibitor with potential antineoplastic activity.CDK4/6 dual inhibitor LY2835219 has been shown in vitro to be a selective ATP-competitive inhibitor of CDK4/6 that inhibits phosphorylation of the Rb tumor suppressor protein and thereby induces G1 cell cycle arrest.Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition,thereby arresting the cell cycle in the G1 phase,suppressing DNA synthesis and inhibiting cancer cell growth.LY2835219 is being investigated in a phase I clinical trial and in a clinical trial for the treatment of mantle cell lymphoma.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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