LY2409881 CAS：946518-60-1

LY2409881 is a selective inhibitor of IκB kinase β(IKK2;IC50=30 nM).1 It inhibits IKK1 and other common kinases at≥10-fold higher concentrations.1 LY2409881 has been shown to suppress constitutively activated NF-κB and to induce apoptosis in lymphoma cells both in vitro and in preclinical mouse models of B and T cell lymphoma both as a single agent and in combination with histone deacetylase inhibitors.

msds---LY2409881