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Home > products > fluorescent-dyes > No-ROS-Rox-derivatives > leucettine-l41

Leucettine L41,cas:1112978-84-3

(5Z)-5-(1,3-benzodioxol-5-ylmethylene)-3,5-dihydro-2-(phenylamino)-4H-imidazol-4-one

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-XASYS-00095 5mg 458.00
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R-XASYS-00095 10mg 875.00
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Product description

Leucettine L41 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), DYRK2, CDC-like kinase 1 (CLK1), and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 μM, respectively).It also inhibits GSK3α/β and Pim1 with IC50 values of 0.41 and 4.1 μM, respectively. It inhibits phosphorylation of the serine/arginine (SR) protein 9G8 by DYRK2, DYRK3, CLK1, CLK2, and CLK4 and inhibits TNF-α-induced SRp75 and SRp55 phosphorylation in human microvascular endothelial cells when used at concentrations ranging from 0.1 to 10 μM

Leucettine L41,cas:1112978-84-3

Appearance N/A
Molecular Weight N/A
Purity >90%
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 1 year
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