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L-685458 CAS:292632-98-5

L-685458

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-3378 10mg 720.00
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R-C-3378 20mg 1250.00
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Product description

L-685458 is a potent transition state analog(TSA)γ-secretase inhibitor(GSI).L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17nM,shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3nM, respectively.L-685458 can be used for the research of alzheimer is disease(AD)and cancers.Our products are only suitable for scientific research experiments,not for clinical experiments and human body.


Appearance N/A
Molecular Weight N/A
purity >95%
CAS 292632-98-5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 2 years
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