KU 55933 CAS：587871-26-9

KU-55933 is an ATM inhibitor,which blocks the phosphorylation of Akt induced by insulin and insulin-like growth factor I in cancer cells that exhibit abnormal Akt activity. Moreover,KU-55933 inhibits cancer cell proliferation by inducing G(1)cell cycle arrest.It does so through the downregulation of the synthesis of cyclin D1,a protein known to be elevated in a variety of tumors. 

msds---KU 55933