Imidazole Ketone Erastin,cas:1801530-11-9
2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[5-[2-(1H-imidazol-1-yl)acetyl]-2-(1-methylethoxy)phenyl]-4(3H)-quinazolinone
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-XASYS-00082 | 5mg | 580.00 | + Add to cart |
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| R-XASYS-00082 | 10mg | 985.00 | + Add to cart |
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Product description
Imidazole ketone erastin(C35H35ClN6O5,655.1) is an inducer of ferroptosis.It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter.Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large B cell lymphoma (DLBCL) cells in a concentration-dependent manner, as well as reduces glutathione (GSH) levels in these cells (IC50 = 34 nM)Imidazole ketone erastin is an inducer of ferroptosis.levels in these cells (IC50 = 34 nM)
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| Purity | >90% |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 3 weeks |
| Stability | 1 year |
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Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
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