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Imidazole Ketone Erastin,cas:1801530-11-9

2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[5-[2-(1H-imidazol-1-yl)acetyl]-2-(1-methylethoxy)phenyl]-4(3H)-quinazolinone

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-XASYS-00082 5mg 580.00
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R-XASYS-00082 10mg 985.00
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Product description

Imidazole ketone erastin(C35H35ClN6O5,655.1) is an inducer of ferroptosis.It inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter.Imidazole ketone erastin increases production of lipid reactive oxygen species (ROS) in SUDHL6 diffuse large B cell lymphoma (DLBCL) cells in a concentration-dependent manner, as well as reduces glutathione (GSH) levels in these cells (IC50 = 34 nM)Imidazole ketone erastin is an inducer of ferroptosis.levels in these cells (IC50 = 34 nM)

Imidazole Ketone Erastin,cas:1801530-11-9

Appearance N/A
Molecular Weight N/A
Purity >90%
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 1 year
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