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Halofuginone CAS No.55837-20-2
Halofuginone CAS No.55837-20-2
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2612 | 25mg | 280.00 | + Add to cart |
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| R-R-2612 | 50mg | 480.00 | + Add to cart |
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Product description
Halofuginone (RU-19110)/CAS No.55837-20-2, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
| Appearance | N/A |
|---|---|
| Molecular Weight | 414.68 |
| Purity | >90% |
| CAS | 55837-20-2 |
| Formula | C16H17BrClN3O3 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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