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GW406108X CAS No.1644443-92-4
GW406108X CAS No.1644443-92-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2141 | 5mg | 280.00 | + Add to cart |
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| R-R-2141 | 10mg | 460.00 | + Add to cart |
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Product description
GW406108X/CAS No.1644443-92-4 is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK.
| Appearance | N/A |
|---|---|
| Molecular Weight | 400.21 |
| Purity | >90% |
| CAS | 1644443-92-4 |
| Formula | C20H11Cl2NO4 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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msds of GW406108X CAS No.1644443-92-4 Related Product
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