GSK8612 CAS:2361659-62-1
GSK8612
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-2136 | 50mg | 425.00 | + Add to cart |
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R-C-2136 | 100mg | 725.00 | + Add to cart |
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R-C-2136 | 200mg | 1150.00 | + Add to cart |
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Product description
GSK8612 is a potent and highly selective TBK1 inhibitor.GSK8612 inhibited recombinant TBK1 with an average pIC50 of 6.8 in a biochemical functional assay. In THP1 cells,GSK8612 was able to inhibit secretion of interferon beta(IFNβ)in response to dsDNA and cGAMP,the natural ligand for STING.GSK8612 is a TBK1 small molecule inhibitor displaying an excellent selectivity profile and therefore represents an ideal probe to further dissect the biology of TBK1 in models of immunity,neuroinflammation,obesity,or cancer.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 2 years |
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