Items-$0.00
Email:sales@ruixibiotech.com
Tel.:02988811435
GNE-987 CAS No.2417371-71-0
GNE-987 CAS No.2417371-71-0
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2477 | 1mg | 560.00 | + Add to cart |
|
| R-R-2477 | 2mg | 980.00 | + Add to cart |
|
|
|
||||
Product description
GNE-987/CAS No.2417371-71-0 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 exhibits picomolar cell BRD4 degradation activity (DC50=0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50=4.7 and 4.4 nM, respectively). GNE-987 incorporates a potent BET binder/inhibitor, a VHL-binding fragment, and a ten methylene spacer moiety. GNE-987 can be used in PROTAC-Antibody Conjugate (PAC).
| Appearance | N/A |
|---|---|
| Molecular Weight | 1096.31 |
| Purity | >90% |
| CAS | 2417371-71-0 |
| Formula | C56H67F2N9O8S2 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
msds of GNE-987 CAS No.2417371-71-0 Related Product
RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com
