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EN450 CAS No.793719-01-4
EN450 CAS No.793719-01-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1284 | 10mg | 220.00 | + Add to cart |
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| R-R-1284 | 25mg | 470.00 | + Add to cart |
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Product description
EN450/CAS No.793719-01-4 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. EN450 interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D. EN450 induces the ternary complex formation between UBE2D and NFKB1. EN450 exerts its anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism.
| Appearance | N/A |
|---|---|
| Molecular Weight | 288.75 |
| Purity | >90% |
| CAS | 793719-01-4 |
| Formula | C11H13ClN2O3S |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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