DSPE-TK-PEG-TAT(YGRKKRRQRRRC)

DSPE-TK-PEG-YGRKKRRQRRRC,DSPE-thioketal-PEG-YGRKKRRQRRRC,DSPE provides a double eighteen carbon hydrophobic chain that can stably embed into the membrane structure of liposomes or nanomicelles,enhancing the physical stability of the carrier.TK (thioketal)acts as a reactive oxygen species(ROS)sensitive linker,breaking in highly oxidative environments(such as tumors and inflammatory tissues)to achieve targeted drug release. PEG increases water solubility and biocompatibility,prolongs blood circulation time,and reduces clearance of the reticuloendothelial system.TAT peptide(YGRKKRRQRRRC)is a transmembrane peptide derived from HIV transcription activator,rich in alkaline amino acids,which can efficiently penetrate cell membranes and blood-brain barriers,significantly enhancing drug accumulation in the central nervous system and tumor cells.This product is only for scientific research and cannot be used on the human body.

msds---DSPE-TK-PEG-TAT(YGRKKRRQRRRC)