PEI-PEG-TAT(linear)

TAT-PEG2K-PEI25K,PEI-PEG-TAT,PEI-PEG-YGRKKRRQRRRC,Linear PEI as a cationic polymer, can compress nucleic acid drugs such as DNA and RNA through electrostatic interactions to form stable nanocomposites,and exert proton sponge effect to promote endosome escape and improve transfection efficiency.PEG modification can shield the positive charge on the surface of PEI,significantly reduce cytotoxicity and immunogenicity, and prolong the circulation time of the carrier in vivo.TAT peptide(YGRKKRRQRRR)has strong cell penetration ability and can actively mediate the carrier to cross the cell membrane and blood-brain barrier,improving the uptake efficiency of target cells(such as tumor cells and neurons).This product is only for scientific research and cannot be used on the human body.

msds----PEI-PEG-TAT(linear)