DSPE-PEG(2000)-DBCO lipid

Lipid nanoparticles containing DSPE-PEG(2000)-DBCO can be used to deliver mRNA vaccines in a targeted and stable manner.The DBCO group allows for easy labeling or attachment of biomolecules, which can be beneficial in various biochemistry or molecular biology applications, such as studying protein interactions or cellular uptake mechanisms.
The combination of a stable lipid core (DSPE) and a hydrophilic PEG chain helps in encapsulating therapeutics and improving their circulation time, ultimately leading to enhanced efficacy and reduced toxicity.
By functionalizing the DBCO groups with azide-conjugated targeting moieties (like antibodies, peptides, or imaging agents),you can create specifically targeted delivery systems that can selectively bind to disease sites (e.gtumors).

msds of DSPE-PEG(2000)-DBCO lipid