DSPE-PEG-pHis

DSPE-PEG-poly(l-histidine),poly(l-histidine)-PEG-DSPE,pHis-PEG-DSPE,DSPE provides a hydrophobic double chain fatty acid structure that can be stably embedded in the lipid bilayer of liposomes and nanoparticles.PEG segments endow the material with good water solubility and spatial flexibility,reducing non-specific protein adsorption and prolonging in vivo circulation time. The pKa of the imidazole side chain at the end pHis is about 6.0,and protonation occurs in weakly acidic environments, exhibiting typical pH responsive characteristics.

msds----DSPE-PEG-pHis