DOTAP:PC:Chol (10:60:30 molar ratio)

DOTAP:PC:Chol/1,2-dioleoyl-3-trimethylammonium-propane (chloride salt):L-alpha-Phosphatidylcholine:Cholesterol(10:60:30 molar ratio) used in drug delivery systems. The balance of charge and stability allows for effective delivery vehicles, capable of encapsulating and protecting therapeutic agents.The presence of DOTAP allows for complexation with DNA or RNA, while the structural role of PC ensures the formulation of stable vesicles. Cholesterol further stabilizes these vesicles against physical and chemical stresses, improving their delivery efficiency in biological systems.Researchers might use this mixture to study lipid bilayer characteristics, such as fluidity and phase behavior, or as models for more complex biological membranes.

msds of dotap-pc-chol-10-60-30-molar-ratio