CZC-25146 CAS:1191911-26-8
CZC-25146
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-1410 | 50mg | 400.00 | + Add to cart |
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R-C-1410 | 100mg | 600.00 | + Add to cart |
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R-C-1410 | 200mg | 900.00 | + Add to cart |
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Product description
CZC-25146 is a second generation inhibitor of LRRK2 with excellent potency and selectivity.In a time-resolved fluorescence resonance energy transfer assay, CZC-25146 shows potent inhibition of both recombinant human wild type LRRK2 and G2019S mutant LRRK2 with IC50 values of 4.76nM and 6.87nM,respectively.CZC-25146 is selective against LRRK2.When treated with 184 different protein kinases and one lipid kinase,CZC-25146 inhibits only five of them with high potency including PLK4,GAK,TNK1,CAMKK2 and PIP4K2C.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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