CZC-25146 CAS:1191911-26-8
CZC-25146
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-1410 | 50mg | 400.00 | + Add to cart |
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| R-C-1410 | 100mg | 600.00 | + Add to cart |
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| R-C-1410 | 200mg | 900.00 | + Add to cart |
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Product description
CZC-25146 is a second generation inhibitor of LRRK2 with excellent potency and selectivity.In a time-resolved fluorescence resonance energy transfer assay, CZC-25146 shows potent inhibition of both recombinant human wild type LRRK2 and G2019S mutant LRRK2 with IC50 values of 4.76nM and 6.87nM,respectively.CZC-25146 is selective against LRRK2.When treated with 184 different protein kinases and one lipid kinase,CZC-25146 inhibits only five of them with high potency including PLK4,GAK,TNK1,CAMKK2 and PIP4K2C.
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com


