CDDO-dhTFEA CAS No.1191265-33-4

CDDO-dhTFEA (RTA dh404)/CAS No.1191265-33-4 is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats.

msds of CDDO-dhTFEA CAS No.1191265-33-4