BTdCPU CAS:1257423-87-2

BTdCPU is an activator of HRI.The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma.Combination therapy with rapamycin,an mTOR inhibitor, and BTdCPU,an activator of HRI,demonstrated additive effects on apoptosis in dex-resistant cells.Thus,specific activation of the eIF2α kinase HRI is a novel therapeutic target in MM that can augment current treatment strategies.

msds---BTdCPU