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AS2863619 CAS No.2241300-51-4
AS2863619 CAS No.2241300-51-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2364 | 5mg | 330.00 | + Add to cart |
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| R-R-2364 | 10mg | 540.00 | + Add to cart |
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Product description
AS2863619/CAS No.2241300-51-4 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene.
| Appearance | N/A |
|---|---|
| Molecular Weight | 405.24 |
| Purity | >90% |
| CAS | 2241300-51-4 |
| Formula | C16H14Cl2N8O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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