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AMG-548 dihydrochloride CAS No.2518299-32-4

AMG-548 dihydrochloride CAS No.2518299-32-4

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-R-4486 5mg 380.00
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R-R-4486 10mg 650.00
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Product description

AMG-548 dihydrochloride/CAS No.2518299-32-4, an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ. AMG-548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM). AMG-548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε.

AMG-548 dihydrochloride CAS No.2518299-32-4

Appearance N/A
Molecular Weight 534.48
Purity >90%
CAS 2518299-32-4
Formula C29H29Cl2N5O
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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