A549 membrane package PLGA@DOX

Doxorubicin(DOX)can maximize the efficacy and minimize dose limiting cardiotoxicity by controlled release of PEGylated nanoparticles.Using avidin biotin coupling system,the binding of PEG to PLA nanoparticles was controlled. The particle size was about 130 nm,and DOX was loaded to 5% (wt/wt).The encapsulation of nanoparticles will not affect the efficacy of DOX.

msds---A549 membrane package PLGA@DOX