3-Deazaneplanocin A,cas:102052-95-9
5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-XASYS-00501 | 5mg | 1633.00 | + Add to cart |
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| R-XASYS-00501 | 10mg | 2586.00 | + Add to cart |
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Product description
3-Deazaneplanocin A(C12H14N4O3,262.3) is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase.It has been shown to deplete EZH2 levels and to inhibit trimethylation of lysine 27 on histone H3 in cultured human acute myeloid leukemia (AML) HL-60 and OCI-AML3 cells and in primary AML cells in a dose-dependent manner (0.2-1μM).
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| Purity | >90% |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 3 weeks |
| Stability | 1 year |
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