Catalog |
name |
Description |
price |
R-M-478 |
Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt |
Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt,a broad-spectrum MMP substrate |
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R-M-482 |
Ac-Ala-Ala-Ala-Ala-OMe |
Substrate for the esterolytic activity of elastase, as the enzyme cleaves the methyl ester of Ac-Ala4-OMe much more rapidly than an amide bond. |
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R-M-483 |
Ac-Ala-Ala-Ser(PO₃H₂)-Pro-Arg-pNA trifluoroacetate salt |
Ac-AApSPR-pNA, excellent chromogenic substrate for the human peptidyl-prolyl cis/trans isomerase Pin1 (kcat/Km = 9300 mM⁻¹s⁻¹) and its yeast homolog Ess1 (kcat/Km = 12000 mM⁻¹s⁻¹). |
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R-M-763 |
Dansyl-Ala-Arg-OH trifluoroacetate salt |
Dansyl-Ala-Arg-OH trifluoroacetate salt is a Fluorescent substrate for carboxypeptidase M. Because the substrate and the cleavage product Dansyl-Ala-OH are equally fluorescent, the product has to be extracted with chloroform. |
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R-M-764 |
Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH trifluoroacetate salt |
Highly sensitive fluorescence resonance energy transfer (FRET) substrate for neutral endopeptidase (NEP or neprilysin EC 3.4.24.11) (Km = 45 μM, kcat = 59 min⁻¹, kcat/Km = 1.3 min⁻¹μM⁻¹). Enzymatic activity can be monitored with an excitation wavelength of 342 nm and an emission wavelength of 562 nm. |
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R-M-800 |
Fluorogenic Human CMV Protease Substrate trifluoroacetate salt |
The FRET substrate Dabcyl-RGVVNASSRLA-Edans has been synthesized to develop a fluorescence-based assay of human cytomegalovirus proteinase. It is cleaved specifically at the Ala-Ser bond thereby liberating the C-terminal peptide-EDANS fragment from the proximity quenching effect of the DABCYL group. This represents the first fluorescence-based assay of the herpes virus proteases and permits the characterization of potential inhibitors. |
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R-M-817 |
DABCYL-Υ-Abu-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH₂ |
DABCYL-Υ-Abu-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH₂ is a selective fluorogenic (FRET) matrix metalloproteinase (MMP) substrate. |
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R-M-1038 |
DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂ |
DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂ is a Highly soluble fluorogenic (FRET) matrix metalloproteinase (MMP) substrate . The fluorescence increase is measured using an excitation wavelength of 340 nm and an emission wavelength of 485 nm. Due to the relatively high emission wavelength of EDANS the substrate allows convenient measurement of MMP activity in complex biological media like synovial fluid and culture medium. |
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R-M-819 |
DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt |
The fluorogenic HIV-1 protease substrate DABCYL-Gaba-SQNYPIVQ-EDANS consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm. |
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R-M-826 |
Endotoxin Substrate acetate salt,CAS : 68223-96-1 |
Boc-LGR-pNA, a chromogenic substrate for horseshoe crab clotting enzyme, which is used in quantitative assays of endotoxin. |
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