Product custom-synthesis-phospholipid-synthesis-customization

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Catalog	name	Description	price
R-C-5999	3S-PtdIns(3,4,5)P3, diC16	PtdIns(3,4,5)P3 3-phosphothioate, diC16 (3S-PtdIns(3,4,5)P3, diC16) is a synthetic PI(3,4,5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6000	3S-PtdIns(3,4,5)P3, diC8	PtdIns(3,4,5)P3 3-phosphothioate, diC8 (3S-PtdIns(3,4,5)P3, diC8) is a water-soluble, synthetic PI(3,4,5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate.P-3S908 shows 90% inhibition of PTEN at 0.4µM.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6001	4A3-SC8 CAS：1857340-78-3	4A3-SC8 is an ionizable lipid dendrimer used in generating lipid nanoparticles (LNPs) for RNA delivery. Incorporation of differently charged lipids (DODAP, DOTAP, or PA) into 4A3-SC8 LNPs allow for selective delivery of RNA to the liver,lungs,or spleen.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6002	93-O17O	93-O17O is an ionizable lipid used in lipid nanoparticles(LNPs).LNP compositions have proven effective as transport vehicles into cells and/or intracellular compartments for biologically active substances such as small molecule drugs,proteins and nucleic acids.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6003	93-O17S CAS：2227008-67-3	93-O17S is a lipidoid used for generating lipid nanoparticles to deliver RNA,peptides,and nucleotides. 93-O17S LNPs were able to deliver Cre recombinase mRNA in mice.In addition,LNPs were able to deliver the Cre recombinase protein and Cas9:single-guide RNA into cells for genome editing.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6004	9A1P9	9A1P9 is a multi-tail ionizable phospholipid which promotes membrane destabilization and cargo release, enhancing mRNA delivery and gene editing.Lipid nanoparticles prepared with 9A1P9 exhibited 40- to 965-fold higher in vivo mRNA delivery efficacy compared to DOPE and DSPC.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6005	9Z-Octadecenyl phosphate CAS：7722-71-6	9Z-Octadecenyl phosphate,ammonium salt (ODP)is a fatty alcohol phosphate analog of oleoyl-LPA.It does not activate or inhibit Ca2+-mobilization in LPA1-3 expressing RH7777 cells. However,it potentiates the agonist activity of oleoyl-LPA on LPA receptor expressing cells.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6006	AA3-DLin CAS：2832061-33-1	AA3-DLin is an ionizable lipid used in generating lipid nanoparticles(LNPs)for RNA delivery.Unlike LNPs formulated with other ionizable lipids,AA3-DLin LNPs performed best with higher proportions of phospholipid and lower cholesterol(40:40:25:0.5 AA3-DLin/DOPE/cholesterol/DMG-PEG).AA3-DLin containing LNPs were able to deliver full-length SARS-COV2 spike protein mRNA to BALB/c mice and generate a strong immune response.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6007	ALC-0159 1849616-42-7	ALC-0159 is a PEG/lipid conjugate(PEGylated lipid),specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid,O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide).It is a non-ionic surfactant by its nature.The product is only suitable for scientific research experiments and is not intended for human or clinical use.	price>
R-C-6008	d5-D-myo-Phosphatidylinositol 3,4,5-trisphosphate DiC16	Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis.	price>

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