Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-C-289	Tf-PEG-CDDP	Objective to prepare transferrin (TF) modified cisplatin long circulating liposomes (TF peg CDDP) and investigate its physical properties and in vitro release characteristics.Methods blank liposomes were prepared by membrane dispersion ultrasonic method,and loaded with cisplatin by ammonium sulfate gradient method.TF peg CDDP was prepared by linking transferrin with terminal active group of dspe-peg2000-mal;The encapsulation efficiency of TF peg CDDP was determined by UV VIS spectrophotometer.The particle size was determined by laser scattering particle size analyzer and its properties were observed by transmission electron microscope.The sustained release ability of cisplatin liposomes in vitro was detected by dialysis method.Results TF peg CDDP was round vesicle like structure, slightly uneven in size,and the average particle size was 200 nm,The average entrapment efficiency was (78.222±5.4086)%,and the stability was acceptable.The in vitro release test showed that TF peg CDDP had better sustained-release ability than CDDP.Conclusion TF peg CDDP has sustained-release ability and is an effective cisplatin targeted preparation.	price>
R-C-290	DSPE-PEG-SWCNTs	There are three types of short and high-purity carbon nanotubes:TNSS,tnssh and tnssc.TNSS is prepared by mechanical cutting and then dispersing high-purity carbon nanotubes.Tnssh and tnssc are hydroxylated and carboxylated derivatives of TNSS,respectively.They were prepared by oxidation in H2SO4 solution with different KMnO4 concentration and different temperature.	price>
R-C-001	DPPE-PEG-cRGD	Irgd peptide is a cyclic peptide composed of nine amino acids.It binds with AV integrins first,and then enzymolysis produces crgdk/R.it interacts with neuropilin-1 to promote the tissue permeation of drugs.It has the function of targeting tumor and tumor permeation.Integrin αVβ 3 is a kind of cell adhesion molecule highly expressed on the surface of some tumor cells and tumor neovascularization endothelial cells,but hardly expressed on the surface of normal tissues and mature blood vessels. Integrin α V β 3 can realize active targeting through mutual recognition with RGD sequences in natural ligands.	price>
R-C-295	DSPE-TK-PEG-NPC	Dspe-tk-peg-npc is a kind of linear cross functional polyethylene glycol reagent, which contains DSPE phospholipids and NPC.It is an effective self-assembly reagent for the preparation of polyethylene glycol liposomes or micelles,and also provides a NPC group molecule coupled with mercaptan.It is often used for targeted drug delivery.Lipid bilayers enhance drug resistance.Peg provides stealth function,prolongs the half-life of blood circulation,reduces nonspecific protein binding or cell adhesion,and acidic groups are used to bind target molecules,including antibodies,aptamers,proteins and peptides.	price>
R-C-296	DSPE-TK-PEG-cRGD	The crgd in phospholipid peg crgd is a five membered cyclic peptide, which can be used for passive targeting,active targeting research and drug delivery of micelles and vesicles.DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides.	price>
R-C-303	DOPE-PEG-cRGDyk	There are many kinds of CGD cyclic peptides,including C (RGDfK),C (rgdfc),C (rgdyk),C(rgdyc),etc.,but C (RGDfK) and C (RGDfc) are commonly used and have good targeting.1,2-dioleoyl-sn-glycoro-3-phosphoethanolamine (DOPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol, which has hydrophilic and hydrophobic properties.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.	price>
R-C-418	DSPE-PEG-ZnDPA	Fluorescent cell apoptosis targeting probe(zndpa)uses the high affinity of zndpa and phosphatidylserine to detect apoptotic cells or bacteria through the specific binding of apoptotic cell everted phosphatidylserine (or phosphatidylserine on the surface of bacteria).Phospholipid zndpa can target apoptosis,bacterial infection,inflammation related diseases,tumor and so on.	price>
R-C-861	DMSP	Osmolar dimethylsulfonylpropionate(DMSP)of algae is the main precursor of marine dimethyl sulfide(DMS).DMS is a volatile sulfur compound,which affects atmospheric chemistry and global climate.DMSP may play an important role in the microbial ecology and biogeochemistry of the marine surface.The sulfur in DMSP is effectively bound to bacterial proteins(mainly methionine),and DMSP seems to be the main source of sulfur in marine planktonic bacteria.	price>
R-C-3322	DSPE-PEG550-RGD(ARG-GLY-ASP)	Phospholipid polyethylene glycol RGD can be used for passive targeting,active targeting and drug delivery of micelles and vesicles.DSPE is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides.	price>
R-C-3323	DSPE-PEG750-RGD(ARG-GLY-ASP)	Phospholipid polyethylene glycol RGD can be used for passive targeting,active targeting and drug delivery of micelles and vesicles.DSPE is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides.	price>

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