Catalog name Description price
R-M3-043 CD 2665,CAS:170355-78-9 CD 2665 is a synthetic compound of interest in the field of dermatological research, where it is used to study the regulation of retinoid-responsive genes. As an agonist of the retinoic acid receptors (RARs), it aids in dissecting the pathways through which retinoids impact cellular differentiation and proliferation. In vitro studies harness CD 2665 to observe changes in skin cell morphology and to analyze gene expression profiles in response to retinoic acid receptor activation. Furthermore, this compound provides a means to explore the signaling mechanisms that are involved in the homeostasis of skin tissue. price>
R-M3-044 Capsiate,CAS:205687-01-0 Capsiate is a non-pungent analog of capsaicin that has been found in C. annuum and has diverse biological activities. It inhibits Src in, as well as VEGF-induced proliferation of and tube formation by, human umbilical vein endothelial cells (HUVECs) when used at concentrations ranging from 5 to 25 µM. Capsiate activates transient receptor potential vanilloid 1 (TRPV1) in HEK293 cells expressing the human channel (EC50 = 290 nM) and induces licking and biting behaviors, markers of nociception, in mice. Topical application of capsiate reduces antigen-induced increases in ear thickness in a mouse model of passive cutaneous anaphylaxis and decreases epidermal thickness and eosinophil and mast cell infiltration in a mouse model of atopic dermatitis. Capsiate (10 mg/kg) decreases body weight gain and perirenal fat weight, as well as increases oxygen consumption, fat oxidation, and carbohydrate oxidation, in a mouse model of ad libitum feeding-induced weight gain. price>
R-M3-045 CGP 55845 Hydrochloride,CAS:149184-22-5 CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC50 of 6 nM. CGP55845 hydrochloride can be used for neurological research. price>
R-M3-046 CGS 9343B,CAS:109826-27-9 CGS 9343B is a CaM antagonist that inhibits CaM-stimulated cAMP phosphodiesterase activity. price>
R-M3-047 2-Chlorobenzo[d]thiazol-7-ol,CAS:96489-54-2 2-Chlorobenzo[d]thiazol-7-ol,CAS:96489-54-2/2-Chloro-1,3-benzothiazol-7-ol is an organic compound that can be used in various chemical research applications, potentially including studies on pharmacology or materials science. price>
R-M3-048 8-Chloro Diclosulam,CAS:207801-50-1 8-Chloro Diclosulam,CAS:207801-50-1 is a derivative of diclosulam, a non-selective herbicide used primarily for weed control in agricultural settings. price>
R-M3-049 4-Chloro Desloratadine,CAS:133330-63-9 4-Chloro Desloratadine is an antihistamine that is derived from desloratadine, which is the active metabolite of loratadine. It is commonly used to relieve allergy symptoms, such as runny nose, sneezing, and itchy or watery eyes, by blocking the action of histamine in the body. price>
R-M3-050 (E)-N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)but-2-enamide (E)-N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)but-2-enamide may exhibit biological activity and could be investigated for applications in medicinal chemistry, such as:Antimicrobial activity.Antitumor properties,owing to the relevance of quinoline derivatives in cancer treatment. price>
R-M3-051 7-Chloro Epinastine Hydrochloride,CAS:80012-45-9 7-Chloro Epinastine Hydrochloride is a derivative of the antihistamine compound Epinastine, primarily used in the treatment of allergic conditions such as allergic conjunctivitis.Antihistamine Activity: Primarily works as a selective H1 receptor antagonist, blocking the effects of histamine and thus alleviating allergy symptoms such as itching, redness, and swelling. price>
R-M3-052 (2R,3S)-1-Chloro-2-hydroxy-3-[(benzyloxycarbonyl)amino]-4-(phenylthio)butane (2R,3S)-1-Chloro-2-hydroxy-3-[(benzyloxycarbonyl)amino]-4-(phenylthio)butane/CAS:220365-46-8 is an optically active derivative with potential applications in pharmaceutical chemistry due to its specific functional groups that may exhibit significant biological activity. Pharmaceutical Chemistry: Due to its complex structure, the compound may be useful in the synthesis of biologically active compounds, especially in the field of medicinal chemistry targeting enzyme inhibitors or receptor modulators. Synthetic Intermediates: Useful as an intermediate in the synthesis of other nitrogen-containing heterocycles or potentially bioactive compounds. Chiral Syntheses: Can be utilized in studies of optical isomerism and the importance of chirality in drug design. price>