Product fluorescent-dyes-fluorescent-enzyme-substrates

Home > products > fluorescent-dyes> fluorescent-enzyme-substrates

Catalog	name	Description	price
R-C-3601	(Z-Ala-Ala-Ala-Ala)2Rh110	(Z-Ala-Ala-Ala-Ala)2Rh110 is a fluorogenic elastase substrate.Elastase can break down elastin that is an elastic fibre that, together with collagen and can determine the mechanical properties of connective tissue. The neutrophil form breaks down the Outer membrane protein A of E. coli and other Gram-negative bacteria.	price>
R-C-3602	coumarin-SAHA	Suberoylanilide hydroxamic acid(SAHA)is a histone deacetylase(HDAC)inhibitor. Coumarin-Suberoylanilide hydroxamic acid(c-SAHA)is a SAHA derivative where the anilino cap group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC.	price>
R-C-3603	7-hydroxycoumarinyl-a-Linolenate	7-hydroxycoumarinyl-γ-Linolenate is a PLA2 fluorogenic substrate used in the assays with phospholipid and Ca2+.	price>
R-C-3604	4-Methylumbelliferyl a-D-Galactopyranoside-6-sulfate sodium salt	4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate(4-MU-Gal-6S)is a fluorogenic substrate for N-acetylgalactosamine-6-sulphatase(GALNS).4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence intensity increases as pH decreases.	price>
R-C-3605	NFF-3	NFF-3 is a fluorogenic substrate for matrix metalloproteinases(MMPs).NFF-3 is hydrolyzed rapidly by MMP-3(kcat/Km=218,000 s-1M-1)and slowly by MMP-9 (kcat/Km=10,100 s-1M-1) with no significant hydrolysis by MMP-1 or MMP-2, therefore it can be used to differentiate MMP-3 activity from that of other MMPs.	price>
R-C-3606	Naphthol AS-BI-Phosphate	Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases.Naphthol AS-BI-phosphate is cleaved to release the fluorescent moiety naphthol AS-BI(N-ASBI),which can be used to quantify the activity of acid and alkaline phosphatases.	price>
R-C-3607	Ac-LEHD-AMC	Ac-LEHD-AMC is a selective fluorogenic substrate for caspase 9. The caspase 9-induced hydrolysis of Ac-LEHD-AMC results in the release of AMC fluorophore that is detected using an excitation wavelength of ~365 nm and an emission wavelengh of ~450 nm.	price>
R-C-3608	Dnp-PLGMWSR	Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. The activity of MMP-2 and MMP-9 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.	price>
R-C-3609	Bz-FVR-AMC	Bz-FVR-AMC is a fluorogenic substrate for bovine cathepsins S and H, Xenopus endopeptidase XSCEP1, and esterase E-II from B. gabonica venom, among others. 7-amino-4-methylcoumarin (AMC) is released by cleavage of Bz-FVR-AMC and emits fluorescence that can be used to quantify enzyme activity.	price>
R-C-3610	FITC-C6-PLALWAR-Lys(Biotin)-NH2	FITC-C6-PLALWAR-Lys(Biotin)-NH2 is a substrate for matrix metalloproteinase-1 (MMP-1),MMP-2, and MMP-3. It is cleaved by MMP-1,MMP-2 and MMP-3 to release FITC, which emits fluorescence used for quantification of MMP activity.	price>

...