Product synthetic-chemistry-click-chemistry-dbco-tco-azide-etc

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Catalog	name	Description	price
R-M2-9593	DBCO-NOTA	DBCO-NOTA,Dibenzocyclooctyne-NOTA can be used to label biological targeting molecules with radiometals (e.g., gallium-68) for PET imaging.The DBCO-NOTA conjugate allows for the selective labeling of biomolecules without interfering with their biological functions.	price>
R-M-7081	DBCO-C6-NH2	DBCO-C6-NH2 is an analog of DBCO-NH2 with an extended 6-carbon atom spacer arm. The extended 6-carbon atom spacer arm improves its derivatization efficiency and the stability of the yielded conjugates. This spacer arm also improves solubility in organic solvents such as dichloromethane, chloroform, THF, and ethyl acetate. DBCO is commonly used for copper-free Click Chemistry reactions.	price>
R-M-7082	DBCO-SS-NHS	Dibenzocyclooctyne (dbco) was used in the azido alkyne cycloaddition (spaac) reaction without copper ion catalysis. The kinetic constant of the second order reaction was 1.Dbco series products include dbco acid,dbco amine,dbco peg NHS,dbco peg amine, as well as dbco labeled biotin,fluorescent dyes and biochemical small molecules.	price>
R-M2-9621	DOX-TCO	DOX-TCO,Doxorubicin-TCO can design drug delivery systems that enable the drug to be selectively activated or released at tumor sites. This helps reduce systemic toxicity and improve therapeutic efficacy. The TCO moiety allows for bioorthogonal reactions, where the doxorubicin can be selectively released or activated in the presence of specific partners (like tetrazines) within biological systems. This enables very precise timing and location of drug action. Doxorubicin-TCO conjugates are part of ongoing research aimed at improving the delivery methods of chemotherapeutic agents.	price>
R-M2-9622	CPT-TCO	CPT-TCO,Camptothecin-TCO can be designed for various tumor types by incorporating specific ligands on the drug delivery vehicle that are recognized by receptors overexpressed in particular tumors. This increases the localization of the drug to cancer cells while sparing normal tissues. The conjugation of camptothecin with TCO allows for the selective targeting of cancer cells. The camptothecin-TCO can remain inactive until it is brought to the site of the tumor and is reacted with a tetrazine (or another Diels-Alder partner), leading to the release of the active drug form. This reduces systemic toxicity and enhances treatment specificity.Utilizing bioorthogonal reactions not only allows for drug delivery but also enables the potential for tracking the distribution and accumulation of the drug within the body using imaging techniques. This dual function can greatly enhance therapeutic efficacy and patient monitoring during cancer treatment.	price>
R-M2-9623	PTX-TCO	The incorporation of TCO into the paclitaxel molecule provides a way to direct the delivery of the drug to tumor sites. When the TCO is reacted with a Diels-Alder partner, such as a tetrazine, at the site of a tumor, paclitaxel can be released in a controlled manner. This targeting helps to minimize the exposure of non-cancerous tissues to the drug, reducing side effects. The bioorthogonal nature of the TCO moiety allows for the possibility of using imaging agents in conjunction with paclitaxel-TCO conjugates. This dual functionality can enable real-time tracking of drug distribution and bioavailability within the body, helping clinicians monitor the efficacy of chemotherapy treatments.	price>
R-M1-8001	DBCO-PEG350-FA	Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. DBCO-PEG-FA can go Click Chemistry reaction without a needof any catalysts.	price>
R-M1-8003	Dibenzocycolctyne-PEG750-Folic Acid	DBCO-PEG-FA can go Click Chemistry reaction without a needof any catalysts.Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.	price>
R-M2-9648	PTX-N3	PTX-N3,Paclitaxel-N3,Paclitaxel-Azide can be coupled with DBCO or other reactive moieties to create targeted drug delivery systems. This approach allows for the selective delivery of paclitaxel to cancer cells, potentially enhancing anticancer efficacy while minimizing side effects.Paclitaxel-N3 can be conjugated with fluorescent dyes or imaging agents for the study of drug distribution and cellular uptake. This can provide insights into the pharmacokinetics and pharmacodynamics of paclitaxel in vivo.	price>
R-M1-8015	TCO-sialic acid	TCO-sialic acid，trans-cyclooctene -sialic acid a bifunctional chelator.	price>

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