Product protein-crosslinkers-bioconjugation-products

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Catalog	name	Description	price
R-M2-9630	Biotin-dual target Pt^4+ complex	A biotin-modified dual-target tetravalent platinum complex is a promising concept that holds the potential for targeted cancer therapy. By combining the cytotoxic properties of platinum drugs with the targeting capabilities of biotin, such complexes could enhance therapeutic efficacy and reduce side effects associated with traditional chemotherapeutics. Further research is needed to fully understand the pharmacodynamics, pharmacokinetics, and potential therapeutic window of these innovative compounds.	price>
R-M2-9632	Pt (IV) drugs with thiol-biotin function	Pt(IV) drugs modified with thiol-biotin,Platinum(IV) drugs with thiol-biotin function can be designed to selectively target cancer cells that overexpress biotin receptors, enhancing the efficacy while minimizing off-target effects. The attachment of imaging agents to the Pt(IV) scaffolds with biotin functionality can be a strategy for tracking drug distribution and localization in vivo. These complexes can be combined with other therapeutic agents, such as small molecules or other chemotherapeutics, to exploit synergistic effects in cancer treatment.	price>
R-M2-9689	Biotin-Dopamine	Biotin-dopamine is used in the formulation of nanoparticles for the targeted delivery of drugs, particularly in cancer therapy.Biotin-dopamine conjugates can be utilized to design sensitive biosensors that identify biomolecules with high specificity, such as proteins or nucleic acids.The strong affinity of biotin for streptavidin allows for the use of biotin-dopamine in imaging studies where specific tissues or cells need to be labeled.	price>
R-M2-9695	SAM(S-adenosylmethionine)-Biotin	Biotin-conjugated SAM can be used to study methyltransferases and their substrates, allowing for more straightforward detection and analysis of enzymatic activity. Researchers can biotinylate proteins or other biomolecules with SAM attached, facilitating the study of methylation patterns in proteins. The conjugate may be used in drug delivery systems targeting methylation-related disease pathways—leveraging the specificity of biotin to guide drugs to specific tissues. It can be employed to trace and study methylation pathways in cells, helping elucidate the roles of SAM in various physiological and pathological contexts.	price>
R-M2-9696	SAH(S-adenosyl homocysteine)-Biotin	Biotin-conjugated SAH can be used to study the inhibition of methyltransferase enzymes since its presence can help elucidate the kinetics and regulation of SAM-dependent reactions in vitro or in vivo. Researchers can track changes in methylation patterns in cells by introducing biotin-conjugated SAH into the cellular environment, allowing for assessments of methylation status and related metabolic effects.	price>
R-M2-9721	Biotin-HRP	Biotin-HRP/Biotin-horseradish peroxidase is a conjugate of biotin (a vitamin) and horseradish peroxidase (HRP, an enzyme). It is widely used in biochemical detection and signal amplification systems, particularly in ELISA, Western blotting, immunohistochemistry, and streptavidin-based assays.	price>
R-M2-9836	Biotin-Resveratrol	Biotin-Resveratrol is a biotinylated polyphenol conjugate, where resveratrol, a natural antioxidant and polyphenolic compound, is covalently linked to biotin. This conjugation allows the bioactive resveratrol molecule to be used in biotin–avidin/streptavidin-based systems for targeted delivery, immobilization, or detection. Applications: Targeted drug delivery systems – conjugation to nanoparticles or liposomes via biotin–avidin chemistry. Affinity assays and biosensors – immobilization of resveratrol for receptor or enzyme studies. Molecular imaging and tracking – visualization of resveratrol distribution. Theranostics – combining antioxidant effects with targeted delivery.	price>
R-M2-9852	Biotin-Leucine	Biotin-Leucine/L-Leucine,Biotin labed is a biotinylated derivative of the essential amino acid leucine, in which a biotin moiety is covalently attached to leucine. This conjugate combines the biotin functionality (for high-affinity binding to streptavidin/avidin systems) with the biological and structural role of leucine, enabling targeted detection, immobilization, or delivery. Applications: Biotinylated peptide synthesis for affinity purification or pull-down assays. Streptavidin-based detection systems in imaging or diagnostics. Molecular probes for studying leucine-mediated interactions or uptake. Custom bioconjugation in drug delivery and biomaterials research.	price>
R-M2-9856	Biotin-Osimertinib	Biotin-Osimertinib is a biotinylated derivative of osimertinib, a third-generation EGFR tyrosine kinase inhibitor (EGFR-TKI) used in cancer therapy. The biotin tag enables avidin/streptavidin binding, allowing osimertinib to be used in affinity assays, target identification, and drug delivery studies while retaining its kinase inhibitory functionality. Applications: Target engagement studies to identify osimertinib binding partners. Affinity purification or pull-down assays using streptavidin systems. Cellular uptake and biodistribution tracking of osimertinib derivatives. Development of biotin-based drug delivery platforms.	price>
R-M2-9857	Biotin-c16-Ceramide	Biotin-C16-Ceramide is a biotinylated sphingolipid derivative, in which biotin is covalently attached to C16-ceramide. This conjugate combines the bioactive lipid ceramide, involved in apoptosis and cell signaling, with a biotin tag for streptavidin-based detection, enrichment, or delivery applications. Applications: Lipid trafficking and metabolism studies using biotin–streptavidin systems. Cell signaling research on ceramide-mediated apoptosis and stress pathways. Affinity purification or pull-down assays for ceramide-binding proteins. Targeted delivery in drug discovery and nanomedicine.	price>

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