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R-C-4677 OSu-Glu-vc-PAB-MMAE OSu-Glu-VC-PAB-MMAE is a part of antibody-coupled drug (drug-linker conjugate for ADC), which has anticancer activity. It is connected by MMAE (a kind of tubulin inhibitor) and OSu-Glu-VC-PAB. price>
R-M1-8795 mPEG2000-WGYPHSPARWAWG mPEG2000-WGYPHSPARWAWG is a single functional peptide compound that can be used for targeting cells, drug delivery, and other research. price>
R-M-5343 BDP 576/589 NHS-Ester BDP 576/589 (a BODIPY™ 576/589 analog) is a boron dipyrromethene dye. This hydrophobic dye has high quantum yield and long excited-state lifetime (about 5 nanoseconds). It can be used for measuring fluorescence lifetime and fluorescence polarization and in two-photon laser scanning microscopy.This reagent is an activated N-hydroxysuccinimide ester of the dye with reactivity to primary and secondary amino groups. price>
R-C-4678 DSPE-HYD-PEG2K-carboxyl methyl 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Hyd-polyethylene glycol-carboxyl methyl can be prepared to be a PH sensitive liposome conjugated with peptides, antibodies, or proteins which contain Amine groups on the surface. price>
R-M1-8796 mPEG2000-WGYPHSWLWARS mPEG2000-WGYPHSWLWARS is a single functional peptide compound that can be used for targeting cells, drug delivery, and other research. price>
R-M-5344 BDP 576/589 carboxylic acid,cas:150173-78-7 BDP 576/589, a boron dipyrromethene dye, is an analog of BODIPY™ 576/589 dye. This hydrophobic dye with emission in the orange spectrum range has high quantum yield and high molar extinction coefficient. It is suitable for experiments measuring fluorescence lifetime and fluorescence polarization. This fluorophore can be used whether in wide-field and confocal microscopy or in multiphoton microscopy because of its high two-photon absorption cross-section.This derivative is a carboxylic acid (contains a free COOH-group). It can be used as a reference control and for conjugation with an amino group after activation with carbodiimides. price>
R-C-4679 PAMAM G5-PEG-Vancomycin Vancomycin kills bacteria by inhibiting their growth and reproduction.This drug interferes with the synthesis of cell wall by interfering with peptidoglycan,a key component in the structure of bacterial cell wall,and inhibits the production of phospholipids and peptides in the cell wall.Polyamidoamine(PAMAM)dendrimers are hyperbranched polymers with unparalleled molecular uniformity,narrow molecular weight distribution,defined size and shape characteristics and a multifunctional terminal surface. price>
R-M1-cs8797 ROS responsive liposomes loaded with CE6+ML385+L-arginine By combining these three components (CE6, ML385, and L-arginine) within ROS responsive liposomes, it is possible to create a targeted drug delivery system that responds to specific oxidative conditions found in the body. The release of the cargo can be triggered by ROS, leading to local therapeutic effects. price>
R-M-5345 BDP 576/589 tetrazine BDP 576/589 dye can be used in various methods based on measuring fluorescence lifetime. Similarly to other dyes of the BDP family, BDP 576/589 has strong hydrophobic properties and is suitable for labeling non-polar and lypophilic biomolecules and their subsequent visualization by fluorescent microscopy, including two-photon microscopy.This reagent is a tetrazine derivative that can be conjugated with various strained dienophiles such as trans-cyclooctenes and cyclopropenes. This reaction (TCO ligation) is considered to be one of the best bioconjugation reactions because it is very fast and selective in physiological conditions and does not require additional catalyzers, so it is not toxic in vitro and in vivo. price>
R-C-4680 PLGA-pp-PEG Poly(lactic-co-glycolic acid)-polyethylene glycol Copolymer-Use in drug delivery, controlled release, drug formulation,tissue scaffolding,implant,self-assembled nanoparticles. Biodegradable polymers have tunable hydrolytic stability and degradability from weeks to years depending on molecular weight,lactide to glycolide ratio. price>
R-M1-cs8798 ROS responsive liposomes loaded with CE6+ML385 The combination of CE6 and ML385 in ROS responsive liposomes can be particularly useful in targeting and treating diseases or conditions characterized by high ROS levels, such as certain cancers, inflammatory disorders, and oxidative stress-related diseases. price>
R-M-5346 BDP 564/570 carboxylic acid,cas:150173-89-0 BDP 564/570 is a fluorophore with the emission in orange part of the spectrum. The dye is pretty hydrophobic. It can be used for the labeling of lipids, oligonucleotides, peptides, and many other large and small molecules.Free carboxylic acid can be used in peptide synthesis as an N-terminal monomer. An NHS ester, with a pre-activated carboxy group, is also available. price>
R-C-4681 DOPE-PEG12-(KIAALKE)4-CONH2 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol has both hydrophilicity and hydrophobility and is the excellent liposome formation material that can be used for drug delivery,gene transfection and vaccine delivery as well.Moreover,these material can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies,peptides. price>
R-M1-cs8799 ROS responsive liposomes loaded with CE6 ROS responsive liposomes loaded with CE6 (chlorin e6) are a type of drug delivery system designed to specifically target and respond to reactive oxygen species (ROS) in the body. Upon destabilization, the liposomes release the CE6 into the surrounding tissues. The released CE6 can then undergo a photochemical reaction when activated by specific wavelengths of light, generating highly reactive singlet oxygen species. This localized generation of singlet oxygen can induce cell death, making it particularly suitable for photodynamic therapy (PDT) applications. By specifically targeting and releasing the CE6 in ROS-rich areas, ROS responsive liposomes loaded with CE6 can enhance the therapeutic efficacy of photodynamic therapy while minimizing off-target effects. price>
R-M-5347 BDP 564/570 NHS ester,cas:150173-90-3 BDP 564/570 is a lypophilic dye with orange emission. This NHS ester is useful for the labeling of amine containing biomolecules, including amine-modified oligonucleotides. price>
R-C-4682 DOPE-PEG12-(EIAALEK)4-CONH2 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol has both hydrophilicity and hydrophobility and is the excellent liposome formation material that can be used for drug delivery,gene transfection and vaccine delivery as well.Moreover,these material can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies,peptides. price>
R-M1-8800 Dabcyl-IDASMQINLANKADE-Edans Dabcyl-IDASMQINLANKADE-Edans is a peptide sequence labeled with two fluorescent molecules, Dabcyl and Edans. These molecules are often used as FRET (Fluorescence Resonance Energy Transfer) pairs to study molecular interactions, enzyme activity, and protease assays. Dabcyl (4-[(4-dimethylamino)phenylazo]benzoic acid) is a dark quencher molecule that efficiently quenches the fluorescence of Edans. In the absence of enzymatic activity, the Dabcyl and Edans molecules remain in close proximity, resulting in fluorescence quenching. The Dabcyl-IDASMQINLANKADE-Edans construct is commonly used in enzyme kinetic assays, drug discovery research, and studying protein-protein interactions. The peptide sequence within this construct can be modified to target different protease enzymes of interest. price>
R-M-5348 SF488-NHS In addition to its superior fluorescence characteristics (such as high brightness and super light stability), the design of SFTM fluorophores also simplifies the fluorescence labeling and detection process. SFTM fluorophores can be directly used in aqueous working buffer without adding any organic solvent.The elimination of organic solvents can not only simplify the labeling and detection process, but also provide additional protection for molecules from some harsh organic solvents.In addition, SFTM fluorophores provide a variety of chemical reactions and / or bioactive parts, which can be directly used to label, image and detect various molecules and particles.These fluorophores range from ultraviolet to near-infrared and can be used for in vitro and in vivo imaging. price>
R-M1-8801 MIL-47(V)-NH2 MIL-47(V)-NH2 is a metal organic framework material (MOF) with functionalized ligands of vanadium (V) metal ions and amino (NH2) functional groups.These materials have attracted significant attention due to their high surface areas, tunable properties, and potential applications in gas storage, catalysis, and drug delivery, among others. price>
R-M-5349 SF488-Maleimide In addition to its superior fluorescence characteristics (such as high brightness and super light stability), the design of SFTM fluorophores also simplifies the fluorescence labeling and detection process. SFTM fluorophores can be directly used in aqueous working buffer without adding any organic solvent. The elimination of organic solvents can not only simplify the labeling and detection process, but also provide additional protection for molecules from some harsh organic solvents. In addition, SFTM fluorophores provide a variety of chemical reactions and / or bioactive parts, which can be directly used to label, image and detect various molecules and particles. These fluorophores range from ultraviolet to near-infrared and can be used for in vitro and in vivo imaging. price>