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R-C-4039 DSPE-polyethylene glycol750-azide DSPE-PEG-azide (DSPE-PEG-N3) is lipid-PEG conjugate with terminated azide. Azide reacts readily with alkyne or cycloocytne in aqueous solution with or without copper catalyst.DSPE-PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility.Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery,gene transfection and vaccine delivery as well. price>
R-R-5719 Tenofovir alafenamide CAS No.:383365-04-6 Tenofovir alafenamide/CAS No.:383365-04-6 is a nucleoside analog reverse transcriptase inhibitor used primarily for the treatment of chronic hepatitis B virus infection and HIV-1 infection. It is a prodrug of tenofovir, designed to improve renal safety and enhance antiviral efficacy compared to its predecessor, tenofovir disoproxil fumarate. price>
R-C-4040 DSPE-PEG350-OH 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility.Polyethylene glycol (PEG) compounds contain a polyether unit,They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. price>
R-R-5720 (3R,4R)-3-Amino-4-hydroxy-tetrahydropyran CAS No.:1350734-61-0 (3R,4R)-3-Amino-4-hydroxy-tetrahydropyran/CAS No.:1350734-61-0 is a chiral compound with significant importance in various scientific fields. This compound is characterized by its unique stereochemistry, which plays a crucial role in its chemical behavior and biological activity. The presence of both amino and hydroxy functional groups makes it a versatile intermediate in organic synthesis. price>
R-C-4041 DSPE-polyethylene glycol550-OH 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility.Polyethylene glycol (PEG) compounds contain a polyether unit,They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. price>
R-R-5721 (3S,4S)-3-Amino-4-hydroxy-tetrahydropyran CAS No.:1240390-32-2 (3S,4S)-3-Amino-4-hydroxy-tetrahydropyran/CAS No.:1240390-32-2 is a chiral compound with significant importance in organic chemistry and pharmaceutical research. This compound features a tetrahydropyran ring, which is a six-membered ring containing one oxygen atom. The presence of both amino and hydroxy functional groups makes it a versatile intermediate in various chemical reactions and synthesis processes. price>
R-C-4042 hydroxyl-PEG750-DSPE 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility.Polyethylene glycol (PEG) compounds contain a polyether unit,They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. price>
R-R-5722 (1R,5S,6S)-Tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate CAS No.:273206-92-1 (1R,5S,6S)-Tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate CAS No.:273206-92-1.The mode of action of (1R,5S,6S)-Tert-butyl 6-amino-3-azabicyclo[31It is known that the compound is synthesized via a palladium-catalyzed cyclopropanation of maleimides with n-tosylhydrazones . The interaction of this compound with its potential targets and the resulting changes are subjects of ongoing research. price>
R-C-4043 DSPE-PEG350-SH 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. price>
R-R-5723 4-Aminobenzoic-2,6-D2 acid CAS No.:118872-62-1 The primary target of 4-Aminobenzoic-2,6-D2 acid/CAS No.:118872-62-1 (also known as para-aminobenzoic acid or PABA) is the folate synthesis pathway in many human pathogens . PABA is an essential nutrient for these pathogens but is dispensable for humans . It is also used as a precursor for the synthesis of various antimicrobial and cytotoxic agents . price>
R-C-4044 DSPE-polyethylene glycol550-SH 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. price>
R-R-5724 5-Amino-N-(4-(bis(5-amino-2-methylphenyl)methyl)phenyl)-2-methylbenzenesulfonamide CAS No.:1226500-0 5-Amino-N-(4-(bis(5-amino-2-methylphenyl)methyl)phenyl)-2-methylbenzenesulfonamide/CAS No.:1226500-00-0 is a complex organic compound characterized by its multiple amino groups and a sulfonamide group. price>
R-C-4045 Thiol-PEG750-DSPE 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. price>
R-R-5725 tert-Butyl 8-amino-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carboxylate CAS No.:939043-41-1 tert-Butyl 8-amino-4,5-dihydro-1H-benzo[c]azepine-2(3H)-carboxylate/CAS No.:939043-41-1 is a complex organic compound that belongs to the class of benzoazepines These compounds are known for their diverse biological activities and are often used as intermediates in the synthesis of various pharmaceuticals. price>
R-C-4046 DSPE-PEG350-Alkyne 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group.It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules.It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility,the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion,and the acid group to bioconjugate targeting molecules including antibody,aptamer,protein,and peptide. price>
R-R-5726 Non-PEGylated Magnetic Liposomes Non-PEGylated magnetic liposomes are nanoparticles formed from lipid bilayers that encapsulate drugs and incorporate magnetic materials, typically iron oxides (like magnetite or maghemite). Without polyethylene glycol (PEG) modifications, these liposomes exhibit enhanced interaction with biological systems, potentially leading to faster clearance from circulation. Their size usually ranges from 100 to several hundred nanometers, making them suitable for targeted drug delivery and biomedical applications. The magnetic properties enable controlled drug release and precise targeting via external magnetic fields, making them particularly valuable in cancer therapy, gene delivery, and imaging modalities like MRI. price>
R-C-4047 DSPE-polyethylene glycol550-Alkyne 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. price>
R-R-5727 PEGylated Magnetic Liposomes PEGylated magnetic liposomes are sophisticated nanocarriers composed of lipid bilayers that encapsulate therapeutic agents while incorporating magnetic nanoparticles, such as iron oxide, for enhanced targeting capabilities. The addition of polyethylene glycol (PEG) on the liposomal surface improves biocompatibility, increases circulation time in the bloodstream, and reduces immunogenicity. These liposomes typically range from 100 to 200 nanometers in diameter, enabling efficient drug delivery to specific tissues, particularly in cancer therapy. The magnetic properties allow for targeted delivery and controlled release of encapsulated drugs when subjected to an external magnetic field, enhancing therapeutic efficacy while minimizing side effects. Additionally, the use of PEG helps stabilize the liposomes in biological environments, addressing issues of drug leakage and aggregation. Overall, PEGylated magnetic liposomes represent a promising approach in nanomedicine, combining the advantages of targeted therapy with improved pharmacokinetics for various biomedical applications. price>
R-C-4048 Alkyne-PEG750-DSPE 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-Thiol is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a thiol group. It is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol group for conjugation with thiol-containing molecules. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the acid group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. price>
R-R-5728 Non-PEGylated DOTA Liposomes for Remote Loading Radioactive Divalent Cations DOTA encapsulated liposomes are used for remote loading of radioactive divalent ions such as radioactive copper into the liposomes. Cationic ions will not pass through the membrane if there is no pH gradient. Divalent ion will cross the liposome membrane only when there is a flux of proton across of the lipid membrane. Due to the difference in the pH inside and outside of the liposomes, there will be a constant flux of proton from inside of the liposomes to outside of the liposomes. Due to this flux, divalent cations move in the opposite direction from outside to inside of liposomes. Liposomes are thermodynamically stable structures and not very permeable to divalent cations after they are formed. If there is no pH gradient, the divalent cations cannot move from outside to inside of the liposomes, where they will remain outside and won’t cross the membrane. The driving force for remote loading in proton gradient. The radioactive divalent copper is externally added to the liposomes. The divalent ion passes the membrane using pH gradient method and chelates DOTA. price>