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R-M-1522 (PFR)2-[Rh110] Soybean trypsin inhibitor inhibits trypsin, factor Xa, plasmin, and plasma kallikrein activity in serum-free cell culture media. It does not inhibit metallo-, cysteine, aspartic proteases, or tissue kallikrein (serine proteases).Kallikreins (KLKs) are a large family of secreted serine proteases with either trypsin-like or chymotrypsin-like specificity which carry out many biological functions. The KLK proteases are involved in pathways that regulate skin desquamation, tooth enamel formation, kidney function, seminal liquefaction, synaptic neural plasticity, and brain function. Disruptions in the function of KLK activity has been linked to several pathologies, including respiratory diseases, neurodegeneration, anxiety, schizophrenia, skin-barrier dysfunction, pathological inflammation, and cancer. price>
R-C-3971 FITC-CGSPGWVRC-PEG750-DSPE Targeted polypeptide is a promising delivery ligand with the advantages of good permeability,convenient synthesis,low immunogenicity,low cost and easy modification.CGSPGWVRC is a lung endothelial cell targeted peptide obtained by phage display technology,and its good lung endothelial cell targeting ability has been confirmed by experiments in vitro and in vivo.PEG lipid conjugate DSPE peg is not only widely used as a self-assembly material for anticancer drug delivery,but also as an additive material for surface functionalization of various drug delivery systems. price>
R-R-5651 5-(1h-Pyrazol-4-yl)isophthalic acid CAS No.:1108726-74-4 5-(1h-Pyrazol-4-yl)isophthalic acid/CAS No.:1108726-74-4: a fascinating chemical compound with endless scientific potential. Discover its unique structure and delve into its myriad applications in cutting-edge research. price>
R-M-1526 (RFR)4XB Cell penetrating peptide with a repeating motif of cationic-nonpolar-cationic (C-N-C) residues, such repeating motifs are important features of membrane-penetrating peptides. This peptide is able to enhance the efficacy and uptake of peptide phosphorodiamidate morpholino oligomers (PPMOs) into bacterial cells. PPMOs are synthetic DNA mimics that bind cRNA and inhibit bacterial gene expression, however these antisense oligomers need help crossing the outer membrane of Gram-negative bacteria due to their molecular weight and polar characteristics. Cell penetrating peptide such as this, when attached to antisense oligomers can improve their entry into Gram-negative bacteria and increased their potency by orders of magnitude. price>
R-C-3972 DSPE-PEG350-PLGLAG(TIMP) 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes. price>
R-R-5652 5-(Pyridin-4-yl)isophthalic acid CAS No.:1262962-06-0 5-(Pyridin-4-yl)isophthalic acid/CAS No.:1262962-06-0 is a chemical compound with the molecular formula C13H9NO4 . It is often used as a ligand in the synthesis of various coordination polymers. price>
R-M-1527 (Tos-GFHR)2-[Rh110] Candidate peptide substrate for kallikrein-related peptidase 5 (KLK5). In its intact state this peptide is not fluorescent, however when this substrate peptide is cleaved, Rhodamine 110 is released and thus fluorescence can then be detected.Contains rhodamine 110 group, a widely used red fluorescent tag. The terminal carboxylic acids in this peptide have been activated by the addition of the p-tosyl moiety, allowing for easy addition of functional groups or further peptide residues. price>
R-C-3973 DSPE-polyethylene glycol550-PLGLAG(TIMP) 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes price>
R-R-5653 5-(Pyridin-3-yl)isophthalic acid CAS No.:1264068-70-3 5-(Pyridin-3-yl)isophthalic acid/CAS No.:1264068-70-3 is a versatile chemical compound used in scientific research. Its unique properties make it valuable in various applications, such as catalysis, organic synthesis, and drug development. price>
R-M-1528 Ac-PAL-AMC,CAS : 1431362-79-6 This fluorogenic peptide substrate can be used to monitor 20S Immunoproteasome activity. The peptide is hydrolyzed by the Immunoproteasome ß1i/LMP2 subunit, but not effectively cleaved by constitutive 20S Proteasomes. price>
R-C-3974 PLGLAG(TIMP)-PEG750-DSPE 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes. price>
R-R-5654 4-(Pyrimidin-5-yl)benzoic acid CAS No.:216959-91-0 4-(Pyrimidin-5-yl)benzoic acid/CAS No.:216959-91-0 is a chemical entity that can be associated with various chemical reactions and has potential applications in the synthesis of complex molecules. While the provided papers do not directly discuss 4-(Pyrimidin-5-yl)benzoic acid, they do provide insights into related compounds and their chemical behaviors, which can be extrapolated to understand the properties and reactivity of 4-(Pyrimidin-5-yl)benzoic acid. price>
R-M-1529 ACE2 α1 Helix Sequence IEEQAKTFLDKFNHEAEDLFYQS ACE2 peptidase domain (PD) α1 helix is important for binding SARS-CoV-2-RBD of the Spike (S) protein. The 23 residues selected from the ACE2 α1 helix sequence (IEEQAKTFLDKFNHEAEDLFYQS) specifically recognizes the SARS-CoV-2-RBD with sub-nanomolar binding. Binding by this peptide to the SARS-CoV-2-RBD may block the entry of the virus into the host cell. price>
R-C-3975 DSPE-PEG350-PBA 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-polyethylene glycol-Phenylboric acid is a derivative of nano-phospholipid peg.One end of the peg is connected with one end of DSPE phospholipid and the other end is linked with PBA.DSPE phospholipid attached to one PEG terminus.DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. price>
R-R-5655 6-(1H-pyrazol-1-yl)nicotinic acid CAS No.:253315-22-9 6-(1H-pyrazol-1-yl)nicotinic acid/CAS No.:253315-22-9 is a chemical compound used in scientific research. It possesses diverse applications, including drug development, catalysis, and material synthesis. Its unique structure offers intriguing possibilities for further exploration and innovation. price>
R-M-1530 alpha-Defensin 6,CAS :136661-76-2 This peptide contain 6 conserved disulfide-linked cysteines. In vitro, it has a prominent antimicrobial activities against bacteria, fungi, and certain enveloped viruses. In addition, human and rabbit defensins exert potent cytotoxicity in vitro against various mammalian tumor cells. price>
R-C-3976 DSPE-polyethylene glycol550-Phenylboric acid 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-polyethylene glycol-Phenylboric acid is a derivative of nano-phospholipid peg.One end of the peg is connected with one end of DSPE phospholipid and the other end is linked with PBA.DSPE phospholipid attached to one PEG terminus.DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. price>
R-R-5656 3-(Pyridin-3-yl)benzoic acid CAS No.:4385-77-7 3-(Pyridin-3-yl)benzoic acid/CAS No.:4385-77-7 is a compound that features a pyridine ring attached to a benzoic acid moiety. This structure is significant in the field of coordination chemistry, as it can act as a ligand to form various metal-organic frameworks (MOFs) and coordination polymers with different metals. These compounds are of interest due to their potential applications in areas such as luminescence, magnetism, and gas sorption . price>
R-M-1531 Defensin HNP-3 (human),Cas:136661-76-2 This peptide contain 6 conserved disulfide-linked cysteines. In vitro, it has a prominent antimicrobial activities against bacteria, fungi, and certain enveloped viruses. In addition, human and rabbit defensins exert potent cytotoxicity in vitro against various mammalian tumor cells. price>
R-C-3977 PBA-PEG750-DSPE 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-polyethylene glycol-Phenylboric acid is a derivative of nano-phospholipid peg.One end of the peg is connected with one end of DSPE phospholipid and the other end is linked with PBA.DSPE phospholipid attached to one PEG terminus.DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. price>