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R-R-4865 7-Methylguanosine-d3 7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM. price>
R-C-3196 Funapide CAS:1259933-16-8 Funapide(TV 45070;XEN402)is a potent Sodium Channel Nav1.7 inhibitor.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4866 5-Aza-7-deazaguanine CAS No.67410-64-4 5-Aza-7-deazaguanine/CAS No.67410-64-4 is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides. price>
R-C-3197 ICA-121431 ICA-121431 is a potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23nM respectively).Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4867 N6-Etheno 2-deoxyadenosine CAS No.68498-25-9 N6-Etheno 2-deoxyadenosine/CAS No.68498-25-9 is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues. price>
R-C-3198 PF-05089771 CAS:1235403-62-9 PF-05089771 is a Selective Nav1.7 Inhibitor(IC50=11nM)that interacts with the voltage-sensor domain(VSD)of domain IV,Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4868 CCPA CAS No.37739-05-2 CCPA (2-Chloro-N6-cyclopentyladenosine)/CAS No.37739-05-2 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>
R-C-3199 Raxatrigine (GSK1014802) CAS:934240-30-9 Raxatrigine (GSK1014802) is a novel sodium channel blocker and is an effective anticonvulsant agent. In rats, GSK1014802 (20 - 80 mg/kg p.o.) attenuated the deficit in reversal learning induced by phencyclidine (PCP) in a dose-dependent way, which suggested the potential of GSK1014802 in the treatment of cognitive symptoms of schizophrenia. GSK2 was also a potent inhibitor of human MAO-B with pIC50 value of 7.96 but did not inhibit human MAO-A.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4869 Arabinosylhypoxanthine CAS No.7013-16-3 Arabinosylhypoxanthine/CAS No.7013-16-3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>
R-C-3200 Cisapride (R 51619) CAS:81098-60-4 Cisapride(R 51619,Kaudalit, Kinestase,Prepulsid,Presid,Pridesia,Propulsid) is a nonselective 5-HT4 receptor agonist with gastroprokinetic effects.Our products are only suitable for scientific research experiments,not for clinical experiments and human body. price>
R-R-4870 1-Methylinosine-d3 1-Methylinosine-d3 is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3 to the anticodon of eukaryotic tRNA. price>
R-C-3201 VU591 CAS:1222810-74-3 VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24μM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4871 2-O,4-C-Methyleneuridine CAS No.200435-92-3 2-O,4-C-Methyleneuridine (Compound 15a)/CAS No.200435-92-3 is a bicyclic nucleoside. price>
R-C-3202 NS 309 CAS:18711-16-5 NS309 is a potent and selective activator of human Ca2+ -activated K+ channels of SK and IK types with an EC50 of 150 nM for hSK3 channel,and displays no activity at BK channels. Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4872 4-Sulfocalix[8]arene Hydrate CAS 137407-62-6 4-Sulfocalix[8]arene Hydrate/CAS 137407-62-6 is a polymeric matrix of sulfonated arenes that can be used to deliver enzymes for the treatment of diabetes. It has been shown to increase glucose uptake and decrease glycosylation of proteins, leading to improved insulin sensitivity in diabetic patients. 4-Sulfocalix[8]arene Hydrate is stable in the presence of strong acids and bases, allowing it to be administered orally. The diameter of the polymer can be tuned by changing the ratio between hydroxyl groups and sulfonated arenes. This property allows researchers to control the duration of enzyme release and improve its targeting properties. The polymer has also been shown to bind with fluorescence spectrometry, which may make it useful for detecting chemical reactions or identifying target tissue. price>
R-C-3203 Nateglinide (Starlix) CAS:105816-04-4 Nateglinide(Starlix) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4873 1,4,10-Trioxa-7,13-diazacyclopentadecane CAS No 31249-95-3 1,4,10-Trioxa-7,13-diazacyclopentadecane (TDAP)/CAS No 31249-95-3 is a chemical compound that exists in the form of a stable complex with nitrogen atoms. TDAP is used to investigate thermodynamic properties and transport properties of ionic liquids. It has been shown that TDAP can be detected by positron emission tomography (PET) and electron spin resonance (ESR). TDAP has been used in clinical diagnostics for the detection of fatty acids and piperazine. price>
R-C-3204 TRAM-34 CAS: 289905-88-0 TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd=20nM).Exhibits 200-1500-fold selectivity over KV, BKCa,KCa2, Na+,CRAC and Cl- channels.Suppresses the reactivation of lymphocytes by mitogenic stimuli.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4874 Benzo-12-crown 4-Ether CAS No:14174-08-4 Benzo-12-crown 4-ether/CAS No:14174-08-4 is a chemical compound that belongs to the class of benzo crown ethers. It has an optimum concentration of 0.1 M and is soluble in organic solvents such as chloroform, methanol, ethanol, acetone, ethyl acetate, and tetrahydrofuran. Benzo-12-crown 4-ether has been shown to be a potent inhibitor of the tyrosine kinase activity of icotinib hydrochloride (IH) with a binding constant of 1.5 × 10 M. The molecule adopts a rigid structure due to its benzene ring and four ether groups attached to the phenyl group. The molecular weight is 576 g/mol and it has an optical rotation of +27°. FTIR spectroscopy was used to identify functional groups present in this molecule as well as its ring opening in acidic environments at pH 2. Benzo-12-c price>
R-C-3205 GW 542573X CAS:660846-41-3 GW 542573X is an activator of small-conductance Ca2+-activated K+ channels (KCa2)Our products are only suitable for scientific research experiments,not for clinical experiments and human body. price>