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R-R-4859 3-Deoxyuridine-5-triphosphate trisodium 3-Deoxyuridine-5-triphosphate trisodium (3-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3-Deoxyuridine-5-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM. price>
R-C-3190 Isradipine (Dynacirc) CAS:75695-93-1 Isradipine(PN 200-110)is a potent and selective L-type voltage-gated calcium channel blocker,used to treat high blood pressure. price>
R-R-4860 2-O,4-C-Methylenecytidine CAS No.206055-69-8 2-O,4-C-Methylenecytidine (LNA-C(Bz))/CAS No.206055-69-8 is a bicyclic nucleoside analogue with fixed N-type conformation. 2-O,4-C-Methylenecytidine can be used to synthesize oligonucleotides. 2-O,4-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands. price>
R-C-3191 Dantrolene CAS: 7261-97-4 Dantrolene sodium is a muscle relaxant that acts by abolishing excitation-contraction coupling in muscle cells, probably by action on the ryanodine receptor. price>
R-R-4861 Adenosine-13C10,15N5 CAS No.202406-75-5 Adenosine-13C10,15N5/CAS No.202406-75-5 is the 13C and 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. price>
R-C-3192 Atagabalin CAS:223445-75-8 Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2). price>
R-R-4862 N-6-Methyl-2-deoxyadenosine CAS No.2002-35-9 N-6-Methyl-2-deoxyadenosine/CAS No.2002-35-9 is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>
R-C-3193 NNC 55-0396 CAS:357400-13-6 NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and>100μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4863 Elacytarabine CAS No.188181-42-2 Elacytarabine (CP 4055)/CAS No.188181-42-2 is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. price>
R-R-4864 5-Amino-5-deoxyadenosine CAS No.14365-44-7 5-Amino-5-deoxyadenosine (NH2dAdo; Nsc 238990)/CAS No.14365-44-7 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>
R-C-3195 Barnidipine CAS:104713-75-9 Barnidipine(Mepirodipine)is an L-type calcium antagonist(CaA)with high affinity for[3H]initrendipine binding sites(Ki=0.21nmol/l),has selective action against CaA receptors.Our products are only suitable for scientific research experiments,not for clinical experiments and human body. price>
R-R-4865 7-Methylguanosine-d3 7-Methylguanosine-d3 is the deuterium labeled 7-Methylguanosine. 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM. price>
R-C-3196 Funapide CAS:1259933-16-8 Funapide(TV 45070;XEN402)is a potent Sodium Channel Nav1.7 inhibitor.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4866 5-Aza-7-deazaguanine CAS No.67410-64-4 5-Aza-7-deazaguanine/CAS No.67410-64-4 is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides. price>
R-C-3197 ICA-121431 ICA-121431 is a potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23nM respectively).Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4867 N6-Etheno 2-deoxyadenosine CAS No.68498-25-9 N6-Etheno 2-deoxyadenosine/CAS No.68498-25-9 is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues. price>
R-C-3198 PF-05089771 CAS:1235403-62-9 PF-05089771 is a Selective Nav1.7 Inhibitor(IC50=11nM)that interacts with the voltage-sensor domain(VSD)of domain IV,Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4868 CCPA CAS No.37739-05-2 CCPA (2-Chloro-N6-cyclopentyladenosine)/CAS No.37739-05-2 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>
R-C-3199 Raxatrigine (GSK1014802) CAS:934240-30-9 Raxatrigine (GSK1014802) is a novel sodium channel blocker and is an effective anticonvulsant agent. In rats, GSK1014802 (20 - 80 mg/kg p.o.) attenuated the deficit in reversal learning induced by phencyclidine (PCP) in a dose-dependent way, which suggested the potential of GSK1014802 in the treatment of cognitive symptoms of schizophrenia. GSK2 was also a potent inhibitor of human MAO-B with pIC50 value of 7.96 but did not inhibit human MAO-A.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-R-4869 Arabinosylhypoxanthine CAS No.7013-16-3 Arabinosylhypoxanthine/CAS No.7013-16-3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. price>