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R-C-3073 YU238259 CAS:1943733-16-1 YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.Only for scientific research, not for human body. price>
R-R-4743 Filibuvir CAS No.877130-28-4 Filibuvir/CAS No.877130-28-4 is an orally active, selective non-nucleoside inhibitor of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase (RdRp). Filibuvir binds noncovalently in the thumb II allosteric pocket of NS5B. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM for both isoforms, respectively. Filibuvir preferentially inhibits elongative RNA synthesis and potently decreases viral RNA accumulation. price>
R-C-3074 LTURM34 CAS:1879887-96-3 LTURM34 is a specific DNA-PK inhibitor, 170-fold more selective for DNA-PK activity compared to PI3K activity, with IC50 value of 0.034 μM.Only for scientific research, not for human body. price>
R-R-4744 SMN-C2 CAS No.1446311-56-3 SMN-C2/CAS No.1446311-56-3, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research. price>
R-C-3075 KU-0060648 CAS:881375-00-4 KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM. Only for scientific research, not for human body. price>
R-R-4745 Laflunimus CAS No.147076-36-6 Laflunimus (HR325)/CAS No.147076-36-6 is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. price>
R-C-3076 SU 5205 CAS:3476-86-6 SU5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 9.6 µM.Only for scientific research, not for human body. price>
R-R-4746 Adenine-d CAS No.109923-52-6 Adenine-d/CAS No.109923-52-6 is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. price>
R-C-3077 SU-5408 CAS:15966-93-5 SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and selective inhibitor of VEGFR2 Kinase with IC50 of 70 nM.Only for scientific research, not for human body. price>
R-R-4747 MMV688845 CAS No.2208962-35-8 MMV688845/CAS No.2208962-35-8 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy. price>
R-C-3078 SU 5214 CAS:186611-04-1 SU5214 is a inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 14.8 µM and EGFR with IC50 of 36.7 µm, respectively.Only for scientific research, not for human body. price>
R-R-4748 7-TFA-ap-7-Deaza-dA CAS No.178420-75-2 7-TFA-ap-7-Deaza-dA/CAS No.178420-75-2 is a modified nucleoside. 7-TFA-ap-7-Deaza-dA can be used in the synthesis of deoxyribonucleic acid or nucleic acid. 7-TFA-ap-7-Deaza-dA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-3079 Ranibizumab cas:347396-82-1 Ranibizumab is a monoclonal antibody that inhibits angiogenesis by inhibiting Vascular endothelial growth factor A.Only for scientific research, not for human body. price>
R-R-4749 Methylproamine CAS No.188247-01-0 Methylproamine/CAS No.188247-01-0 is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks. price>
R-C-3080 ACC-789(NVP-ACC789) ACC-789, also known as NVP-ACC789 and ZK-202650, is a potent, selective and orally active inhibitor of the VEGF receptor tyrosine kinases with potential anticancer activity.Only for scientific research, not for human body. price>
R-R-4750 SCR7 CAS No.1533426-72-0 SCR7/CAS No.1533426-72-0 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine. SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine is also a CRISPR/Cas9 enhancer which increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity. price>
R-C-3081 JI-101 CAS NO. 900573-88-8 JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.Only for scientific research, not for human body. price>
R-R-4751 Deoxycytidine triphosphate CAS No.2056-98-6 Deoxycytidine triphosphate (dCTP)/CAS No.2056-98-6 is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. price>
R-C-3082 SU1498 CAS:168835-82-3 SU1498, a powerful inhibitor of KDR (IC50=0.7μM), stimulates accumulation of phosphorylated ERK1/2 in endothelial cells.Only for scientific research, not for human body. price>
R-R-4752 Novobiocin CAS No.303-81-1 Novobiocin (Albamycin)/CAS No.303-81-1 is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity.The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Novobiocin sodium) that retains the same biological activity. price>