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Catalog	name	Description	price
R-R-4828	Fanotaprim CAS No.2120282-75-7	Fanotaprim/CAS No.2120282-75-7 is a dihydrofolate reductase (DHFR) inhibitor with IC50s of 1.57 and 308 nM for tgDHFR (Toxoplasma gondii DHFR) and hDHFR (human DHFR), respectively. Fanotaprim has the potential for the research of toxoplasmosis.	price>
R-C-3159	CGP-42112 CAS:127060-75-7	CGP-42112(CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist.	price>
R-R-4829	Cycloguanil-d6	Cycloguanil-d66 is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor.	price>
R-C-3160	AVE 0991 CAS:304462-19-9	AVE 0991 is a nonpeptide and orally active angiotensin-(1-7)receptor agonist with an IC50 of 21nM.	price>
R-R-4830	Trimethoprim-d3 CAS No.1189923-38-3	Trimethoprim-d3/CAS No.1189923-38-3 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.	price>
R-C-3161	SR-12813 CAS:126411-39-0	SR-12813 is a pregnane X receptor(PXR)agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM.	price>
R-R-4831	Proguanil-d6 hydrochloride	Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.	price>
R-C-3162	Epristeride CAS:119169-78-7	Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2.	price>
R-R-4832	Viltolarsen sodium	Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research.	price>
R-C-3163	AR-231453 CAS:733750-99-7	AR-231453 is a potent and selective small molecule agonis of GPR119 that enhances glucose dependent insulin secretion and glucagon like peptide-1 (GLP-1) release.	price>
R-R-4833	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite CAS No.143774-48-5	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite (compound 1B)/CAS No.143774-48-5 is a phosphoramidite of 5-Fluoro-2-deoxycytidine.	price>
R-C-3164	6-OAU CAS:83797-69-7	6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay.6-OAU(GTPL5846,6-n-octylaminouracil)increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512nM.	price>
R-R-4834	Trifluridine/tipiracil hydrochloride mixture CAS No.733030-01-8	Trifluridine/tipiracil hydrochloride mixture (TAS-102)/CAS No.733030-01-8 is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA.	price>
R-C-3165	Versipelostatin	Versipelostatin is a novel GRP78/Bip molecular chaperone down-regulator of microbial origin that was isolated from the metabolite of Streptomyces versipellis strain 4083-SVS6.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4835	2-Chloroadenosine CAS No.146-77-0	2-Chloroadenosine/CAS No.146-77-0, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent Ki=33 μM) and high-affinity nitrobenzylthioinosine binding (apparent Ki=0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes.	price>
R-R-4836	7-Methylguanosine CAS No.20244-86-4	7-Methylguanosine/CAS No.20244-86-4 is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 µM.	price>
R-C-3167	NCRW0005-F05 CAS:342779-66-2	NCRW0005-F05, first antagonist selective for GPR139 (IC50 value 0.21 uM); a useful tool to study GPR139 pharmacology, especially in combination with the GPR139 agonist JNJ 63533054.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4837	Sangivamycin CAS No.18417-89-5	Sangivamycin (NSC 65346)/CAS No.18417-89-5, a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers.	price>
R-C-3168	BMS-564929 CAS:627530-84-1	BMS-564929 is a novel, highly potent, orally active, nonsteroidal tissue selective androgen receptor (AR) modulator, and this compound has been advanced to clinical trials for the treatment of age-related functional decline. Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4838	3-Methylcytidine CAS No.2140-64-9	3-Methylcytidine/CAS No.2140-64-9, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.	price>

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