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Catalog	name	Description	price
R-R-4818	LSN 3213128 CAS No.1941211-99-9	LSN 3213128/CAS No.1941211-99-9 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.	price>
R-C-3149	Aliskiren (CGP 60536) CAS:173334-57-1	Aliskiren(CGP 60536) is a direct renin inhibitor with IC50 of 1.5nM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-R-4819	Pelitrexol CAS No.446022-33-9	Pelitrexol (AG 2037)/CAS No.446022-33-9 is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice.	price>
R-C-3150	MLN-4760 CAS:305335-31-3	MLN-4760(compound 16)is a potent and selective inhibitor of human angiotensin-converting enzyme 2(ACE2)with IC50 of 0.44nM.MLN-4760 also inhibits bovine carboxypeptidase A(CPDA)with IC50 of 27μM.Our products are only suitable for scientific research experiments,not for clinical experiments and human body.	price>
R-R-4820	Methotrexate metabolite CAS No.19741-14-1	Methotrexate metabolite (DAMPA)/CAS No.19741-14-1, the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent. Methotrexate metabolite is an antimalarial agent, which inhibits the parasite growth with an IC50 of 446 nM against the antifolate-sensitive strain and 812 nM against the highly resistant strain under physiological folate conditions. Methotrexate metabolite is inactive against mammalian cells. Methotrexate metabolite is a minimal inhibitor of dihydrofolate reductase among metabolites of methotrexate .	price>
R-C-3151	Eprosartan CAS:133040-01-4	Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure.	price>
R-R-4821	Trimetrexate glucuronate CAS No.82952-64-5	Trimetrexate glucuronate (NSC 352122)/CAS No.82952-64-5 is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia.	price>
R-C-3152	Moxonidine CAS:75438-57-2	Moxonidine(BDF5895) is a selective agonist at the imidazoline receptor subtype 1.	price>
R-R-4822	Trimethoprim-d9 CAS No.1189460-62-5	Trimethoprim-d9/CAS No.1189460-62-5 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment.	price>
R-C-3153	Imidapril (Tanatril) CAS:89371-37-9	Imidapril(Tanatril)is an inhibitor of angiotensin converting enzyme(ACE).	price>
R-R-4823	Tetroxoprim CAS No.53808-87-0	Tetroxoprim/CAS No.53808-87-0 is an antimicrobial DHFR inhibitor.	price>
R-C-3154	Telmisartan CAS:144701-48-4	Telmisartan is an angiotensin II receptor antagonist that inhibits the angiotensin II AT1 receptor.	price>
R-R-4824	Pyrimethamine-d3 CAS No.1189936-99-9	Pyrimethamine-d3/CAS No.1189936-99-9 is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).	price>
R-C-3155	Fimasartan CAS :247257-48-3	Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure.	price>
R-R-4825	Aditoprime CAS No.56066-63-8	Aditoprime (Aditoprim)/CAS No.56066-63-8, a selective bacterial dihydrofolate reductase (DHFR) inhibitor, inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime inhibits E.coli and L.casei DHFR with IC50 of 47 and 520 nM, respectively. Aditoprime has a broad antimicrobial spectrum, good antibacterial activity and excellent pharmacokinetics.	price>
R-C-3156	Zofenopril CAS:81872-10-8	Zofenopril is an angiotensin-converting enzyme(ACE)inhibitor with an IC50 of 81μM.	price>
R-R-4826	LY309887 CAS No.127228-54-0	LY309887/CAS No.127228-54-0 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity.	price>
R-C-3157	SL910102 CAS:144756-71-8	SL910102 is a nonpeptide angiotensin AT1 receptor antagonist.	price>
R-R-4827	Calcium N5-methyltetrahydrofolate CAS No.26560-38-3	Calcium N5-methyltetrahydrofolate(NSC173328)/CAS No.26560-38-3 is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.	price>
R-C-3158	Sparsentan CAS:254740-64-2	Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM,respectively.	price>

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