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Catalog	name	Description	price
R-R-4713	N-Nitrosodiethylamine-d10 CAS No.1219794-54-3	N-Nitrosodiethylamine-d10/CAS No.1219794-54-3 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.	price>
R-C-3044	ZSTK474 CAS：475110-96-4	ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.	price>
R-C-5834	DSPE-polyethylene glycol550-GGGGK(TAMRA)TILVSRSTQTGRRRRRRRR	DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a lipid molecule that can be incorporated into lipid bilayers, such as liposomes.It provides stability and structure to lipid-based nanostructures.PEG (polyethylene glycol) is a biocompatible and hydrophilic polymer that is often attached to lipids to improve the stability, circulation time, and biocompatibility of liposomes.TAMRA is a commonly used fluorescent dye that can be conjugated to peptides(TILVSRSTQTGRRRRRRRR)or other biomolecules for visualization purposes.The molecular weight of PEGs varies.	price>
R-R-4714	Nogalamycin CAS No.1404-15-5	Nogalamycin/CAS No.1404-15-5 is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer.	price>
R-C-3045	PIK-75 CAS：372196-77-5	PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.	price>
R-R-4715	hDHODH-IN-4 CAS No.1644156-56-8	hDHODH-IN-4/CAS No.1644156-56-8 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8.	price>
R-C-3046	MTI-31 CAS：1567915-38-1	MTI-31 (LXI-15029) is a novel mTORC1/mTORC2 inhibitor with Kd of 0.2 nM in mTOR binding assays and displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.	price>
R-R-4716	5-Methoxyflavone CAS No.42079-78-7	5-Methoxyflavone/CAS No.42079-78-7, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.	price>
R-C-3047	mTOR inhibitor-1 cas:468747-17-3	mTOR inhibitor-1 is a novel inhibitor of mTOR pathway. mTOR inhibitor-1 suppress cells proliferation and induces autophagy.	price>
R-R-4717	WRN inhibitor 4 CAS No.2923009-45-2	WRN inhibitor 4 (example 107)/CAS No.2923009-45-2, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 4 can be used for the research of cancer.	price>
R-C-3048	LY303511 hydrochloride cas:2070014-90-1	LY303511 hydrochloride is a structural analogue of LY294002. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. LY303511 does not inhibit PI3K.	price>
R-R-4718	POL1-IN-1 CAS No.1822358-25-7	POL1-IN-1/CAS No.1822358-25-7 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription.	price>
R-C-3049	GNE-477 CAS:1032754-81-6	GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR.	price>
R-R-4719	ML372 CAS No.1331745-61-9	ML372/CAS No.1331745-61-9 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo.	price>
R-C-3050	LY 303511 CAS:154447-38-8	LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.	price>
R-R-4720	RNase L-IN-1	RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation.	price>
R-C-3051	WYE-125132 (WYE-132) CAS:1144068-46-1	WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).	price>
R-R-4721	Cytarabine triphosphate trisodium CAS No.1179343-17-9	Cytarabine triphosphate (Ara-CTP) trisodiu/CAS No.1179343-17-9, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine.	price>
R-C-3052	INK 128 (MLN0128) CAS:1224844-38-5	INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.	price>
R-R-4722	1,1,1-Trifluoroethyl-PEG4-azide CAS: 1817735-35-5	1,1,1-Trifluoroethyl-PEG4-azide/CAS: 1817735-35-5 is a crosslinker containing an azide group and a trifluoroethyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.	price>

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